TAP rabbit pAb

Cat :A22286

TAP ,A22286, 22286, NXF1, TAP; Nuclear RNA export factor 1; Tip-associated protei

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

TAP Polyclonal Antibody detects endogenous levels of TAP protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human NXF1. AA range:1-50
Uniprot No

Q9UBU9
Alternative names

NXF1; TAP; Nuclear RNA export factor 1; Tip-associated protein; Tip-associating protein; mRNA export factor TAP
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

nuclear RNA export factor 1(NXF1) Homo sapiens This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results
Other

NXF1, Nuclear RNA export factor 1n; Tip-associating protein; mRNA export factor TAP
Mol.Wt (Da)

70182
Concentration

1 mg/ml