TDG rabbit pAb

Cat :A22408

TDG ,A22408, 22408, TDG, G/T mismatch-specific thymine DNA glycosylase, TDG

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

TDG Polyclonal Antibody detects endogenous levels of TDG protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TDG. AA range:31-80
Uniprot No

Q13569
Alternative names

TDG; G/T mismatch-specific thymine DNA glycosylase; Thymine-DNA glycosylase
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

thymine DNA glycosylase(TDG) Homo sapiens The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008],
Other

TDG, G/T mismatch-specific thymine DNA glycosylase; G/T mismatch-specific thymine DNA glycosylase; Thymine-DNA glycosylase
Mol.Wt (Da)

46053
Concentration

1 mg/ml