Rabbit
WB,ELISA
Human,Mouse,Rat
WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-20°C/1 year
TGIF Polyclonal Antibody detects endogenous levels of TGIF protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synthesized peptide derived from the C-terminal region of human TGIF.
Q15583
TGIF1; TGIF; Homeobox protein TGIF1; 5'-TG-3'-interacting factor 1
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
TGFB induced factor homeobox 1(TGIF1) Homo sapiens The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provide
TGIF1, Homeobox protein TGIF1
43044
1 mg/ml
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