Thyroglobulin rabbit pAb

Cat :A22549

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IHC 1:50-200, ELISA 1:10000-20000
Storage

-20°C/1 year
Specificity

The antibody detects endogenous Thyroglobulin
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthetic peptide from human protein at AA range: 2511-2560
Uniprot No

P01266
Alternative names

Thyroglobulin (Tg)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

thyroglobulin(TG) Homo sapiens Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009],
Other

TG, Thyroglobulin (Tg)
Concentration

1 mg/ml