TNNT3 rabbit pAb

Cat :A22731

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB 1:500-2000 ELISA 1:5000-20000

  • Storage

    -20°C/1 year

  • Specificity

    TNNT3 Polyclonal Antibody detects endogenous levels of protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from part region of human protein

  • Uniprot No

    P45378

  • Form

    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    troponin T3, fast skeletal type(TNNT3) Homo sapiens The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein; als

  • Other

    TNNT3, Troponin T, fast skeletal muscle (TnTf) (Beta-TnTF) (Fast skeletal muscle troponin T) (fTnT)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images