Topo IIIβ-1 rabbit pAb

Cat :A22748

Topo,A22748, 22748, TOP2A, DNA topoisomerase 2-alpha, TOP2; DNA topoisomerase II; alpha isozyme

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Topo IIIβ-1 Polyclonal Antibody detects endogenous levels of Topo IIIβ-1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TOP3B. AA range:51-100
Uniprot No

O95985
Alternative names

TOP3B; TOP3B1; DNA topoisomerase 3-beta-1; DNA topoisomerase III beta-1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

topoisomerase (DNA) III beta(TOP3B) Homo sapiens This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013],
Other

TOP3B, DNA topoisomerase 3-beta-1
Mol.Wt (Da)

96662
Concentration

1 mg/ml