Troponin I-C (phospho Ser43) rabbit pAb

Cat :A22899

Troponin,A22899, 22899, TNNI3, Troponin I cardiac muscle, TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-Troponin I-C (S43) Polyclonal Antibody detects endogenous levels of Troponin I-C protein only when phosphorylated at S43.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TNNI3 around the phosphorylation site of Ser43. AA range:11-60
Uniprot No

P19429
Alternative names

TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

troponin I3, cardiac type(TNNI3) Homo sapiens Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008],
Other

TNNI3, Troponin I cardiac muscle
Mol.Wt (Da)

24008
Concentration

1 mg/ml