TRβ1 (phospho Ser142) rabbit pAb

Cat :A22938

TRβ1,A22938, 22938, THRB, Thyroid hormone receptor beta, ERBA2; NR1A2; THR1; Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-TRβ1 (S142) Polyclonal Antibody detects endogenous levels of TRβ1 protein only when phosphorylated at S142.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TR-beta1 around the phosphorylation site of Ser142. AA range:116-165
Uniprot No

P10828
Alternative names

THRB; ERBA2; NR1A2; THR1; Thyroid hormone receptor beta; Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

thyroid hormone receptor beta(THRB) Homo sapiens The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008],
Other

THRB, Thyroid hormone receptor beta
Mol.Wt (Da)

52788
Concentration

1 mg/ml