Tsg 101 rabbit pAb

Cat :A22946

Tsg ,A22946, 22946, TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse,Rat,Monkey
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TSG101. AA range:281-330
Uniprot No

Q99816
Alternative names

TSG101; Tumor susceptibility gene 101 protein; ESCRT-I complex subunit TSG101
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

tumor susceptibility 101(TSG101) Homo sapiens The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008],
Other

TSG101, Tumor susceptibility gene 101 protein
Mol.Wt (Da)

43944
Concentration

1 mg/ml