UTRO rabbit pAb

Cat :A23247

UTRO ,A23247, 23247, UTRN DMDL DRP1, Utrophin (Dystrophin-related protein 1) (DRP-1),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC
Reactivity

Human
Dilution

IHC 1:50-300
Storage

-20°C/1 year
Specificity

UTRO Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from part region of human protein
Uniprot No

P46939
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

utrophin(UTRN) Homo sapiens This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008],
Other

UTRN DMDL DRP1, Utrophin (Dystrophin-related protein 1) (DRP-1)
Concentration

1 mg/ml