Vav3 (phospho Tyr173) rabbit pAb

Cat :A23297

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
Uniprot No

Q9UKW4
Alternative names

VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

vav guanine nucleotide exchange factor 3(VAV3) Homo sapiens This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Other

VAV3, Guanine nucleotide exchange factor VAV3
Mol.Wt (Da)

97776
Concentration

1 mg/ml