YAP (phospho Ser127) rabbit pAb

Cat :A23523

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IF,WB,IHC,ELISA
Reactivity

Human,Mouse,Rat,Monkey
Dilution

IF: 1:50-200 WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-YAP (S127) Polyclonal Antibody detects endogenous levels of YAP protein only when phosphorylated at S127.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human YAP around the phosphorylation site of Ser127. AA range:93-142
Uniprot No

P46937
Alternative names

YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

Yes associated protein 1(YAP1) Homo sapiens This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
Other

YAP1, Yorkie homolog
Mol.Wt (Da)

48755
Concentration

1 mg/ml