β-Arrestin 1 (phospho-Ser412) rabbit pAb

Cat :A23896

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB
Reactivity

Human,Mouse,Rat
Dilution

WB 1:1000-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of Human Mouse Rat β-Arrestin 1 (phospho-Ser412)
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized phosho peptide around human β-Arrestin 1 (Ser412)
Uniprot No

P49407
Alternative names

Beta-arrestin-1 (Arrestin beta-1)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

arrestin beta 1(ARRB1) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],
Other

ARRB1 ARR1, β-Arrestin 1 (Ser412)
Concentration

1 mg/ml