TLR2 rabbit pAb

Cat :A23912

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC
Reactivity

Human,Mouse,Rat
Dilution

IHC: 1:200-500
Storage

-20°C/1 year
Specificity

The antibody detects endogenous TLR2 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Recombinant Protein of TLR2
Uniprot No

O60603
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Polyclonal
Isotype

IgG
Background

toll like receptor 2(TLR2) Homo sapiens The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Concentration

1 mg/ml