DR5 mouse mAb

Cat :A23924

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse
Applications

WB,ICC
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. ICC: 1:100.Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of DR5 and does not cross-react with related proteins.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinitychromatography using epitope-specific immunogen.
Immunogen

Purified recombinant human DR5 protein fragments expressed in E.coli
Uniprot No

O14763
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

TNF receptor superfamily member 10b(TNFRSF10B) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009],
Mol.Wt (Da)

48000
Concentration

1 mg/ml