PD-1 (PT1707) mouse mAb

Cat :A23926

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse
Applications

IHC,IF(paraffin section)
Reactivity

Human,Mouse
Dilution

IHC： 1:100-500
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of human PD-1. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
Source/Purification

The antibody was affinity-purified from mouse ascites by affinitychromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human PD-1
Uniprot No

Q15116
Alternative names

PDCD1， PD1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

programmed cell death 1(PDCD1) Homo sapiens This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],
Concentration

1 mg/ml